Blar i forfatter "Kühn, Tilman"

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    • Adherence to the World Cancer Research Fund/American Institute for Cancer Research cancer prevention recommendations and risk of in situ breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Karavasiloglou, Nena; Hüsing, Anika; Masala, Giovanna; van Gils, Carla H.; Fortner, Renée Turzanski; Chang-Claude, Jenny; Huybrechts, Inge; Weiderpass, Elisabete; Gunter, Marc; Arveux, Patrick; Fournier, Agnès; Kvaskoff, Marina; Tjønneland, Anne; Kyrø, Cecilie; Dahm, Christina C.; Vistisen, Helene Tilma; Bakker, Marije F.; Sánchez, María-José; Chirlaque López, María Dolores; Santiuste, Carmen; Ardanaz, Eva; Menéndez, Virginia; Agudo, Antonio; Trichopoulou, Antonia; Karakatsani, Anna; La Vecchia, Carlo; Peppa, Eleni; Palli, Domenico; Agnoli, Claudia; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; Butt, Salma Tunå; Borgquist, Signe; Skeie, Guri; Schulze, Matthias; Key, Timothy; Khaw, Kay-Tee; Tsilidis, Konstantinos K.; Ellingjord-Dale, Merete; Riboli, Elio; Kaaks, Rudolf; Dossus, Laure; Rohrmann, Sabine; Kühn, Tilman (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-02)
      <i>Background</i> - Even though in situ breast cancer (BCIS) accounts for a large proportion of the breast cancers diagnosed, few studies have investigated potential risk factors for BCIS. Their results suggest that some established risk factors for invasive breast cancer have a similar impact on BCIS risk, but large population-based studies on lifestyle factors and BCIS risk are lacking. Thus, ...

    • Alcohol consumption and risk of urothelial cell bladder cancer in the European prospective investigation into cancer and nutrition cohort 

      Botteri, Edoardo; Ferrari, Pietro; Roswall, Nina; Tjønneland, Anne; Hjartåker, Anette; Huerta, José María; Fortner, Renée Turzanski; Trichopoulou, Antonia; Karakatsani, Anna; La Vecchia, Carlo; Pala, Valeria; Pérez-Cornago, Aurora; Sonestedt, Emily; Liedberg, Fredrik; Overvad, Kim; Sánchez, María-José; Gram, Inger Torhild; Stepien, Magdalena; Trijsburg, Laura; Ljungberg, Börje; Johansson, Mikael B.; Kühn, Tilman; Panico, Salvatore; Tumino, Rosario; Bueno-De-Mesquita, Hendrik Bastiaan; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-31)
      Findings on the association between alcohol consumption and bladder cancer are inconsistent. We investigated that association in the European Prospective Investigation into Cancer and Nutrition cohort. We included 476,160 individuals mostly aged 35-70 years, enrolled in ten countries and followed for 13.9 years on average. Hazard ratios (HR) for developing urothelial cell carcinoma (UCC; 1,802 ...

    • Alcohol intake in relation to non-fatal and fatal coronary heart disease and stroke: EPIC-CVD case-cohort study 

      Ricci, Cristian; Wood, Angela; Muller, David; Gunter, Marc J.; Agudo, Antonio; Boeing, Heiner; van der Schouw, Yvonne T.; Warnakula, Samantha; Saieva, Calogero; Spijkerman, Annemieke M.W.; Sluijs, Ivonne; Tjønneland, Anne; Kyrø, Cecilie; Weiderpass, Elisabete; Kühn, Tilman; Kaaks, Rudolf; Sánchez, Maria-Jose; Panico, Salavatore; Agnoli, Claudia; Palli, Domenico; Tumino, Rosario; Engström, Gunnar; Melander, Olle; Bonnet, Fabrice; Boer, Jolanda M.A.; Key, Timothy J.; Travis, Ruth C.; Overvad, Kim; Verschuren, W.M. Monique; Quirós, José Ramón; Trichopoulou, Antonia; Papatesta, Eleni-Maria; Peppa, Eleni; Iribas, Conchi Moreno; Gavrila, Diana; Forslund, Ann-Sofie; Jansson, Jan-Håkan; Matullo, Giuseppe; Arriola, Larraitz; Freisling, Heinz; Lassale, Camille; Tzoulaki, Ioanna; Sharp, Stephen J.; Forouhi, Nita G.; Langenberg, Claudia; Saracci, Rodolfo; Sweeting, Michael; Brennan, Paul; Butterworth, Adam S.; Riboli, Elio; Wareham, Nicholas J.; Danesh, John; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-29)
      Objective To investigate the association between alcohol consumption (at baseline and over lifetime) and non-fatal and fatal coronary heart disease (CHD) and stroke.<p> <p>Design Multicentre case-cohort study.<p> <p>Setting A study of cardiovascular disease (CVD) determinants within the European Prospective Investigation into Cancer and nutrition cohort (EPIC-CVD) from eight European ...

    • Anthropometric and reproductive factors and risk of esophageal and gastric cancer by subtype and subsite: Results from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Sanikini, Harinakshi; Muller, David C.; Sophiea, Marisa; Rinaldi, Sabina; Agudo, Antonio; Duell, Eric J.; Weiderpass, Elisabete; Overvad, Kim; Tjønneland, Anne; Halkjær, Jytte; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Cervenka, Iris; Boeing, Heiner; Kaaks, Rudolf; Kühn, Tilman; Trichopoulou, Antonia; Martimianaki, Georgia; Karakatsani, Anna; Pala, Valeria; Palli, Domenico; Mattiello, Amalia; Tumino, Rosario; Sacerdote, Carlotta; Skeie, Guri; Rylander, Charlotta; López, María-Dolores Chirlaque; Sánchez, Maria-Jose; Ardanaz, Eva; Regnér, Sara; Stocks, Tanja; Bueno-De-Mesquita, Bas; Vermeulen, Roel C.H.; Aune, Dagfinn; Tong, Tammy Y.N.; Kliemann, Nathalie; Murphy, Neil; Chadeau-Hyam, Marc; Gunter, Mark J.; Cross, Amanda J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-03)
      Obesity has been associated with upper gastrointestinal cancers; however, there are limited prospective data on associations by subtype/subsite. Obesity can impact hormonal factors, which have been hypothesized to play a role in these cancers. We investigated anthropometric and reproductive factors in relation to esophageal and gastric cancer by subtype and subsite for 476,160 participants from the ...

    • Association between physical activity and risk of hepatobiliary cancers: A multinational cohort study 

      Baumeister, Sebastian E.; Schlesinger, Sabrina; Aleksandrova, Krasimira; Jochem, Carmen; Jenab, Mazda; Gunter, Marc J.; Overvad, Kim; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Fournier, Agnès; Kühn, Tilman; Kaaks, Rudolf; Pischon, Tobias; Boeing, Heiner; Trichopoulou, Antonia; Bamia, Christina; La Vecchia, Carlo; Masala, Giovanna; Panico, Salvatore; Fasanelli, Francesca; Tumino, Rosario; Grioni, Sara; Bueno-de-Mesquita, Hendrik Bastiaan; Vermeulen, Roel; May, Anne M.; Borch, Kristin Benjaminsen; Oyeyemi, Sunday Oluwafemi; Ardanaz, Eva; Rodríguez-Barranco, Miguel; Chirlaque López, María Dolores; Felez-Nobrega, Mireia; Sonestedt, Emily; Ohlsson, Bodil; Hemmingsson, Oskar; Werner, Mårten; Perez-Cornago, Aurora; Ferrari, Pietro; Stepien, Magdalena; Freisling, Heinz; Tsilidis, Konstantinos K.; Ward, Heather; Riboli, Elio; Weiderpass, Elisabete; Leitzmann, Michael F. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-22)
      <i>Background & Aims</i> - To date, evidence on the association between physical activity and risk of hepatobiliary cancers has been inconclusive. We examined this association in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC).<p><p> <i>Methods</i> - We identified 275 hepatocellular carcinoma (HCC) cases, 93 intrahepatic bile duct cancers (IHBCs), and 164 non-gallbladder ...

    • Association between soft drink consumption and mortality in 10 European countries 

      Mullee, Amy; Romaguera, Dora; Pearson-Stuttard, Jonathan; Viallon, Vivian; Stepien, Magdalena; Freisling, Heinz; Fagherazzi, Guy; Mancini, Francesca Romana; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Kaaks, Rudolf; Boeing, Heiner; Aleksandrova, Krasimira; Tjønneland, Anne; Halkjær, Jytte; Overvad, Kim; Weiderpass, Elisabete; Skeie, Guri; Parr, Christine Louise; Quirós, José Ramón; Agudo, Antonio; Sánchez, María-José; Amiano, Pilar; Cirera, Lluis; Ardanaz, Eva; Khaw, Kay-Tee; Tong, Tammy Y.N.; Schmidt, Julie A.; Trichopoulou, Antonia; Martimianaki, Georgia; Karakatsani, Anna; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; Bueno-de-Mesquita, Hendrik Bastiaan; Verschuren, W.M. Monique; Boer, Jolanda M.A.; Vermeulen, Roel; Ramne, Stina; Sonestedt, Emily; Van Guelpen, Bethany; Holgersson, Pernilla Lif; Tsilidis, Konstantinos K.; Heath, Alicia K.; Muller, David; Riboli, Elio; Gunter, Marc J.; Murphy, Neil (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-03)
      <i>Importance</i> - Soft drinks are frequently consumed, but whether this consumption is associated with mortality risk is unknown and has been understudied in European populations to date.<p><p> <i>Objective</i> - To examine the association between total, sugar-sweetened, and artificially sweetened soft drink consumption and subsequent total and cause-specific mortality.<p><p> <i>Design, ...

    • Association of circulating Vitamin D with colorectal cancer depends on Vitamin D-binding protein isoforms: A pooled, nested, case-control study 

      Gibbs, David Corley; Song, Mingyang; McCullough, Marjorie L.; Um, Caroline Y.; Bostick, Roberd M.; Wu, Kana; Flanders, W. Dana; Giovannucci, Edward; Jenab, Mazda; Brustad, Magritt; Tjønneland, Anne; Perez-Cornago, Aurora; Trichopoulou, Antonia; Tsilidis, Konstantinos K.; Hultdin, Johan; Gurrea, Aurelio Barricarte; Bueno-De-Mesquita, Bas; Mahamat-Saleh, Yahya; Kühn, Tilman; Gunter, Marc; Weiderpass, Elisabete; Fedirko, Veronika (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-15)
      <i>Background</i> - Higher circulating 25-hydroxyvitamin-D [25(OH)D] concentrations are consistently inversely associated with colorectal cancer (CRC) risk in observational studies. However, it is unknown whether this association depends on the functional GC-rs4588*A (Thr436Lys) variant encoding the vitamin D–binding protein-2 (DBP2) isoform, which may affect vitamin D status and bioavailability.< ...

    • Association of leukocyte DNA methylation changes with dietary folate and alcohol intake in the EPIC study 

      Perrier, Flavie; Viallon, Vivian; Ambatipudi, Srikant; Ghantous, Akram; Cuenin, Cyrille; Hernandez-Vargas, Hector; Chajès, Véronique; Baglietto, Laura; Matejcic, Marco; Moreno-Macías, Hortensia; Kühn, Tilman; Boeing, Heiner; Karakatsani, Anna; Kotanidou, Anastasia; Trichopoulou, Antonia; Sieri, Sabina; Panico, Salvatore; Fasanelli, Francesca; Dollé, Martijn; Onland-Moret, Charlotte; Sluijs, Ivonne; Weiderpass, Elisabete; Quirós, José Ramón; Agudo, Antonio; Huerta, José María; Ardanaz, Eva; Dorronsoro, Miren; Tong, Tammy Y.N.; Tsilidis, Konstantinos K.; Riboli, Elio; Gunter, Mark J.; Herceg, Zdenko; Ferrari, Pietro; Romieu, Isabelle (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-02)
      <i>Background</i> - There is increasing evidence that folate, an important component of one-carbon metabolism, modulates the epigenome. Alcohol, which can disrupt folate absorption, is also known to affect the epigenome. We investigated the association of dietary folate and alcohol intake on leukocyte DNA methylation levels in the European Prospective Investigation into Cancer and Nutrition (EPIC) ...

    • Association of menopausal characteristics and risk of coronary heart disease: A pan-European case-cohort analysis 

      Dam, Veerle; van der Schouw, Yvonne T.; Onland-Moret, N. Charlotte; Groenwold, Rolf H.H.; Peters, Sanne A.E.; Burgess, Stephen; Wood, Angela M.; Chirlaque, Maria-Dolores; Moons, Karel G.M.; Oliver-Williams, Clare; Schuit, Ewoud; Tikk, Kaja; Weiderpass, Elisabete; Holm, Marianne; Tjønneland, Anne; Kühn, Tilman; Fortner, Renée T.; Trichopoulou, Antonia; Karakatsani, Anna; La Vecchia, Carlo; Ferrari, Pietro; Gunter, Marc; Masala, Giovanna; Sieri, Sabina; Tumino, Rosario; Panico, Salvatore; Boer, Jolanda M.A.; Verschuren, W.M. Monique; Salamanca-Fernández, Elena; Arriola, Larraitz; Moreno-Iribas, Conchi; Engström, Gunnar; Melander, Olle; Nordendahl, Maria; Wennberg, Patrik; Key, Timothy J.; Colorado-Yohar, Sandra; Matullo, Giuseppe; Overvad, Kim; Clavel-Chapelon, Francoise; Boeing, Heiner; Ramõn Quirõs, Jose; di Angelantonio, Emanuele; Langenberg, Claudia; Sweeting, Michael J.; Riboli, Elio; Wareham, Nicholas J.; Danesh, John; Butterworth, Adam (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-22)
      <i>Background</i> - Earlier age at menopause has been associated with increased risk of coronary heart disease (CHD), but the shape of association and role of established cardiovascular risk factors remain unclear. Therefore, we examined the associations between menopausal characteristics and CHD risk; the shape of the association between age at menopause and CHD risk; and the extent to which these ...

    • Association of Selenoprotein and Selenium Pathway Genotypes with Risk of Colorectal Cancer and Interaction with Selenium Status 

      Fedirko, Veronika; Jenab, Mazda; Méplan, Catherine; Jones, Jeb S.; Zhu, Wanzhe; Schomburg, Lutz; Siddiq, Afshan; Hybsier, Sandra; Overvad, Kim; Tjønneland, Anne; Omichessan, Hanane; Perduca, Vittorio; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Katzke, Verena; Aleksandrova, Krasimira; Trichopoulou, Antonia; Karakatsani, Anna; Kotanidou, Anastasia; Tumino, Rosario; Panico, Salvatore; Masala, Giovanna; Agnoli, Claudia; Naccarati, Alessio; Bueno-De-Mesquita, Bas; Vermeulen, Roel C.H.; Weiderpass, Elisabete; Skeie, Guri; Nøst, Therese Haugdahl; Lujan-Barroso, Leila; Quirós, Jose Ramón; Huerta, José María; Rodríguez-Barranco, Miguel; Barricarte, Aurelio; Gylling, Björn; Harlid, Sophia; Bradbury, Kathryn Erica; Wareham, Nick; Khaw, Kay-Tee; Gunter, Marc J.; Murphy, Neil; Freisling, Heinz; Tsilidis, Kostas; Aune, Dagfinn; Riboli, Elio; Hesketh, John E.; Hughes, David J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-25)
      Selenoprotein genetic variations and suboptimal selenium (Se) levels may contribute to the risk of colorectal cancer (CRC) development. We examined the association between CRC risk and genotype for single nucleotide polymorphisms (SNPs) in selenoprotein and Se metabolic pathway genes. <i>Illumina Goldengate</i> assays were designed and resulted in the genotyping of 1040 variants in 154 genes ...

    • Baseline and lifetime alcohol consumption and risk of differentiated thyroid carcinoma in the EPIC study 

      Sen, Abhijit; Tsilidis, Konstantinos K.; Allen, Naomi E.; Rinaldi, Sabina; Appleby, Paul N.; Almquist, Martin; Schmidt, Julie A.; Dahm, Christina C.; Overvad, Kim; Tjønneland, Anne; Rostgaard-Hansen, Agnetha L.; Clavel-Chapelon, Françoise; Baglietto, Laura; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Katze, Verena A.; Boeing, Heiner; Trichopoulou, Antonia; Tsironis, Christos; Lagiou, Pagona; Palli, Domenico; Pala, Valeria; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.; Hjartåker, Anette; Lund, Eiliv; Weiderpass, Elisabete; Quirós, J. Ramón; Agudo, Antonio; Sánchez, Mariá-José; Arriola, Larraitz; Gavrila, Diana; Gurrea, Aurelio Barricarte; Tosovic, Ada; Hennings, Joakim; Sandström, Maria; Romieu, Isabelle; Ferrari, Pietro; Zamora-Ros, Raul; Khaw, Kay-Tee; Wareham, Nicholas J.; Riboli, Elio; Gunter, Marc; Franceschi, Silvia (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-27)
      Background: Results from several cohort and case–control studies suggest a protective association between current alcohol intake and risk of thyroid carcinoma, but the epidemiological evidence is not completely consistent and several questions remain unanswered.<p> <p>Methods: The association between alcohol consumption at recruitment and over the lifetime and risk of differentiated thyroid carcinoma ...

    • Circulating copper and zinc levels and risk of hepatobiliary cancers in Europeans 

      Stepien, Magdalena; Hughes, David J.; Hybsier, Sandra; Bamia, Christina; Tjønneland, Anne; Overvad, Kim; Affret, Aurélie; His, Mathilde; Boutron-Ruault, Marie-Christine; Katzke, Verena; Kühn, Tilman; Aleksandrova, Krasimira; Trichopoulou, Antonia; Lagiou, Pagona; Orfanos, Phlippos; Palli, Domenico; Sieri, Sabina; Tumino, Rosario; Ricceri, Fulvio; Panico, Salvatore; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Weiderpass, Elisabete; Lasheras, Cristina; Bonet Bonet, Catalina; Molina-Portillo, Elena; Dorronsoro, Miren; Huerta, José María; Barricarte, Aurelio; Ohlsson, Bodil; Sjöberg, Klas; Werner, Mårten; Shungin, Dmitry; Wareham, Nick; Khaw, Kay-Tee; Travis, Ruth C.; Freisling, Heinz; Cross, Amanda J.; Schomburg, Lutz; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-02)
      Background:<br>Copper and zinc are essential micronutrients and cofactors of many enzymatic reactions that may be involved in liver-cancer development. We aimed to assess pre-diagnostic circulating levels of copper, zinc and their ratio (Cu/Zn) in relation to hepatocellular carcinoma (HCC), intrahepatic bile duct (IHBD) and gall bladder and biliary tract (GBTC) cancers.<br>Methods:<br>A nested ...

    • Circulating Isovalerylcarnitine and Lung Cancer Risk: Evidence from Mendelian Randomization and Prediagnostic Blood Measurements 

      Smith-Byrne, Karl; Cerani, Agustin; Guida, Florence; Zhou, Sirui; Agudo, Antonio; Aleksandrova, Krasimira; Barricarte, Aurelio; Barranco, Miguel Rodríguez; Bochers, Christoph H.; Gram, Inger Torhild; Han, Jun; Amos, Christopher I.; Hung, Rayjean J.; Grankvist, Kjell; Nøst, Therese Haugdahl; Imaz, Liher; Chirlaque-López, María Dolores; Johansson, Mikael; Kaaks, Rudolf; Kühn, Tilman; Martin, Richard M.; McKay, James D.; Pala, Valeria; Robbins, Hilary A.; Sandanger, Torkjel M; Schibli, David; Schulze, Matthias B.; Travis, Ruth C.; Vineis, Paolo; Weiderpass, Elisabete; Brennan, Paul; Johansson, Mattias; Richards, J Brent (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-04)
      Background: Tobacco exposure causes 8 of 10 lung cancers, and identifying additional risk factors is challenging due to confounding introduced by smoking in traditional observational studies.<p> <p>Materials and Methods: We used Mendelian randomization (MR) to screen 207 metabolites for their role in lung cancer predisposition using independent genome-wide association studies (GWAS) of blood ...

    • Circulating Metabolites Associated with Alcohol Intake in the European Prospective Investigation into Cancer and Nutrition Cohort 

      van Roekel, Eline H.; Trijsburg, Laura; Assi, Nada; Carayol, Marion; Achaintre, David; Murphy, Neil; Rinaldi, Sabina; Schmidt, Julie A.; Stepien, Magdalena; Kaaks, Rudolf; Kühn, Tilman; Boeing, Heiner; Iqbal, Khalid; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Ricceri, Fulvio; Panico, Salavatore; Peeters, Petra H.; Bueno-De-Mesquita, Hendrik Bastiaan; Ardanaz, Eva; Lujan-Barroso, Leila; Quirós, José Ramón; Huerta, José María; Molina-Portillo, Elena; Dorronsoro, Miren; Tsilidis, Konstantinos K.; Riboli, Elio; Rostgaard-Hansen, Agnetha Linn; Tjønneland, Anne; Overvad, Kim; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Severi, Gianluca; Trichopoulou, Antonia; Karakatsani, Anna; Kotanidou, Anastasia; Håkansson, Anders; Malm, Johan; Weijenberg, Matty P.; Gunter, Marc J.; Jenab, Mazda; Johansson, Mattias; Travis, Ruth C.; Scalbert, Augustin; Ferrari, Pietro (Journal article; Peer reviewed, 2018-05-22)
      Identifying the metabolites associated with alcohol consumption may provide insights into the metabolic pathways through which alcohol may affect human health. We studied associations of alcohol consumption with circulating concentrations of 123 metabolites among 2974 healthy participants from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Alcohol consumption at ...

    • Circulating Vitamin D in relation to cancer incidence and survival of the head and neck and oesophagus in the EPIC cohort 

      Fanidi, Anouar; Muller, David C.; Midttun, Øivind; Ueland, Per Magne; Vollset, Stein Emil; Relton, Caroline; Vineis, Paolo; Weiderpass, Elisabete; Skeie, Guri; Brustad, Magritt; Palli, Domenico; Tumino, Rosario; Grioni, Sara; Sacerdote, Carlotta; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina; Cadeau, Claire; Huerta, José María; Sánchez, María-José; Agudo, Antonio; Lasheras, Cristina; Quirós, J. Ramón; Chamosa, Saioa; Riboli, Elio; Travis, Ruth C; Ward, Heather; Murphy, Neil; Khaw, Kay-Tee; Trichopoulou, Antonia; Lagiou, Pagona; Papatesta, Eleni-Maria; Boeing, Heiner; Kühn, Tilman; Katzke, Verena; Steffen, Annika; Johansson, Anders; Brennan, Paul; Johansson, Mattias (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-04)
      Experimental and epidemiological data suggest that vitamin D play a role in pathogenesis and progression of cancer, but prospective data on head and neck cancer (HNC) and oesophagus cancer are limited. The European Prospective Investigation into Cancer and Nutrition (EPIC) study recruited 385,747 participants with blood samples between 1992 and 2000. This analysis includes 497 case-control pairs ...

    • Citrus intake and risk of skin cancer in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC) 

      Mahamat-Saleh, Yahya; Cervenka, Iris; Al-Rahmoun, Marie; Mancini, Francesca R.; Severi, Gianluca; Ghiasvand, Reza; Veierød, Marit Bragelien; Caini, Saverio; Palli, Domenico; Botteri, Edoardo; Sacerdote, Carlotta; Ricceri, Fulvio; Trichopoulou, Antonia; Peppa, Eleni; La Vecchia, Carlo; Overvad, Kim; Dahm, Christina C.; Olsen, Anja; Tjønneland, Anne; Perez-Cornago, Aurora; Jakszyn, Paula; Grioni, Sara; Schulze, Matthias B.; Skeie, Guri; Lasheras, Christina; Colorado-Yohar, Sandra; RodrÍguez-Barranco, Miguel; Kühn, Tilman; Katzke, Verena A.; Amiano, Pilar; Tumino, Rosario; Panico, Salvatore; Ezponda, Ana; Sonestedt, Emily; Scalbert, Augustin; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-24)
      Citrus intake has been suggested to increase the risk of skin cancer. Although this relation is highly plausible biologically, epidemiologic evidence is lacking. We aimed to examine the potential association between citrus intake and skin cancer risk. EPIC is an ongoing multi-center prospective cohort initiated in 1992 and involving ~ 520,000 participants who have been followed-up in 23 centers from ...

    • Co-benefits from sustainable dietary shifts for population and environmental health: an assessment from a large European cohort study 

      Laine, Jessica E; Huybrechts, Inge; Gunter, Marc J; Ferrari, Pietro; Weiderpass, Elisabete; Tsilidis, Kostas; Aune, Dagfinn; Schulze, Matthias B; Bergmann, Manuela; Boer, Jolanda M A; Agnoli, Claudia; Ericson, Ulrika; Stubbendorff, Anna; Ibsen, Daniel B; Dahm, Christina Catherine; Deschasaux, Mélanie; Touvier, Mathilde; Kesse-Guyot, Emmanuelle; Sánchez Pérez, Maria-Jose; Rodríguez Barranco, Miguel; Tong, Tammy Y N; Papier, Keren; Knuppel, Anika; Boutron-Ruault, Marie-Christine; Mancini, Francesca; Severi, Gianluca; Srour, Bernard; Kühn, Tilman; Masala, Giovanna; Agudo, Antonio; Skeie, Guri; Rylander, Charlotta; Sandanger, Torkjel M; Vineis, Paolo (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-22)
      Background - Unhealthy diets, the rise of non-communicable diseases, and the declining health of the planet are highly intertwined, where food production and consumption are major drivers of increases in greenhouse gas emissions, substantial land use, and adverse health such as cancer and mortality. To assess the potential co-benefits from shifting to more sustainable diets, we aimed to investigate ...

    • Coffee and tea consumption and the contribution of their added ingredients to total energy and nutrient intakes in 10 European countries: Benchmark data from the late 1990s 

      Landais, Edwige; Moskal, Aurélie; Mullee, Amy; Nicolas, Geneviève; Gunter, Marc J.; Huybrechts, Inge; Overvad, Kim; Roswall, Nina; Affret, Aurélie; Fagherazzi, Guy; Mahamat-Saleh, Yahya; Katzke, Verena; Kühn, Tilman; la Vecchia, Carlo; Trichopoulou, Antonia; Valanou, Elissavet; Saieva, Calogero; de Magistris, Maria Santucci; Sieri, Sabina; Braaten, Tonje; Skeie, Guri; Weiderpass, Elisabete; Ardanaz, Eva; Chirlaque, Maria-Dolores; García, José Ramon; Jakszyn, Paula; Rodríguez-Barranco, Miguel; Brunkwall, Louise; Huseinovic, Ena; Nilsson, Lena; Wallström, Peter; Bueno-de-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Aune, Dagfinn; Key, Tim; Lentjes, Marleen; Riboli, Elio; Slimani, Nadia; Freisling, Heinz (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-05)
      Background: <br>Coffee and tea are among the most commonly consumed nonalcoholic beverages worldwide, but methodological differences in assessing intake often hamper comparisons across populations. We aimed to (i) describe coffee and tea intakes and (ii) assess their contribution to intakes of selected nutrients in adults across 10 European countries. <br>Method: <br>Between 1995 and 2000, ...

    • Coffee, tea and melanoma risk: findings from the European Prospective Investigation into Cancer and Nutrition 

      Caini, Saverio; Masala, Giovanna; Saieva, Calogero; Kvaskoff, Marina; Savoye, Isabelle; Sacerdote, Carlotta; Hemmingsson, Oskar; Hammer Bech, Bodil; Overvad, Kim; Tjønneland, Anne; Petersen, Kristina E.N.; Mancini, Francesca Romana; Boutron-Ruault, Marie-Christine; Cervenka, Iris; Kaaks, Rudolf; Kühn, Tilman; Boeing, Heiner; Floegel, Anna; Trichopoulou, Antonia; Valanou, Elisavet; Kritikou, Maria; Tagliabue, Giovanna; Panico, Salvatore; Tumino, Rosario; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Veierød, Marit Bragelien; Ghiasvand, Reza; Lukic, Marko; Quirós, José Ramón; Chirlaque, Maria-Dolores; Ardanaz, Eva; Salamanca Fernández, Elena; Larrañaga, Nerea; Zamora-Ros, Raul; Maria Nilsson, Lena; Ljuslinder, Ingrid; Jirström, Karin; Sonestedt, Emily; Key, Timothy J.; Wareham, Nick; Khaw, Kay-Tee; Gunter, Marc; Huybrechts, Inge; Murphy, Neil; Tsilidis, Konstantinos K.; Weiderpass, Elisabete; Palli, Domenico (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-20)
      In vitro and animal studies suggest that bioactive constituents of coffee and tea may have anticarcinogenic effects against cutaneous melanoma; however, epidemiological evidence is limited to date. We examined the relationships between coffee (total, caffeinated or decaffeinated) and tea consumption and risk of melanoma in the European Prospective Investigation into Cancer and Nutrition (EPIC). EPIC ...

    • Consumption of Fish and Long-chain n-3 Polyunsaturated Fatty Acids Is Associated With Reduced Risk of Colorectal Cancer in a Large European Cohort 

      Aglago, Elom Kouassivi; Huybrechts, Inge; Murphy, Neil; Casagrande, Corinne; Nicolas, Geneviève; Pischon, Tobias; Fedirko, Veronika; Severi, Gianluca; Boutron-Ruault, Marie-Christine; Fournier, Agnès; Katzke, Verena Andrea; Kühn, Tilman; Olsen, Anja; Tjønneland, Anne; Dahm, Christina C.; Overvad, Kim; Lasheras, Cristina; Agudo, Antonio; Sanchez, Maria-Jose; Amiano, Pilar; Huerta, Jose Maria; Ardanaz, Eva; Perez-Cornago, Aurora; Trichopoulou, Antonia; Karakatsani, Anna; Martimianaki, Georgia; Bueno-De-Mesquita, Bas; May, Anne; Derksen, Jeroen W.G.; Hellstrand, Sophie; Ohlsson, Bodil; Wennberg, Maria; Van Guelpen, Bethany; Skeie, Guri; Brustad, Magritt; Weiderpass, Elisabete; Cross, Amanda J.; Ward, Heather; Riboli, Elio; Norat, Teresa; Chajes, Veronique; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-25)
      Background & Aims - There is an unclear association between intake of fish and long-chain n-3 polyunsaturated fatty acids (n-3 LC-PUFAs) and colorectal cancer (CRC). We examined the association between fish consumption, dietary and circulating levels of n-3 LC-PUFAs, and ratio of n-6:n-3 LC-PUFA with CRC using data from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. ...